| Richardson, Brent | Chief Executive Officer | Executive and senior leadership | $336,786 | $1,938 | 2025 |
| Comley, Rebecca | Medical Officer of Health | Other disclosed roles | $291,341 | $1,234 | 2025 |
| Babayan, Aleksey | Director, Foundational Standards | Other disclosed roles | $213,664 | $1,379 | 2025 |
| Stark, Brad | Director, Finance | Finance, procurement and audit | $194,631 | $1,492 | 2025 |
| Williams, Gary | Director, Communications | Communications, marketing and public affairs | $188,843 | $1,379 | 2025 |
| Shah, Syed | Director, Public Health | Other disclosed roles | $160,758 | $591 | 2025 |
| Malenfant, Jason | Medical Officer of Health | Other disclosed roles | $159,133 | $1,024 | 2025 |
| Regan, Michelle | Director, Health Protection | Other disclosed roles | $156,774 | $1,256 | 2025 |
| Wren-Atilola, Hilary | Director, Healthy Communities | Other disclosed roles | $154,343 | $1,236 | 2025 |
| Pajtondziev, Filip | Manager, Infectious Disease and Sexual Health | Corporate administration and operations | $141,015 | $1,084 | 2025 |
| Mitchell, Robyn | Manager, Human Resources | Human resources, labour relations and total rewards | $138,194 | $1,023 | 2025 |
| Campbell, Allison | Manager, Communications | Communications, marketing and public affairs | $135,138 | $1,060 | 2025 |
| Corey, Keith | Manager, Environmental Health | Corporate administration and operations | $129,874 | $1,002 | 2025 |
| Ttimus, Sarah | Director, Public Health | Other disclosed roles | $129,560 | $505 | 2025 |
| Robertson, Eric | Manager, Immunizations and Oral Health | Corporate administration and operations | $127,898 | $983 | 2025 |
| Prentice, James | Supervisor, Finance | Finance, procurement and audit | $127,653 | $495 | 2025 |
| Renn, Deanna | Manager, Healthy Communities | Corporate administration and operations | $127,268 | $983 | 2025 |
| Ovens, Terri-Lynn | Manager, Healthy Growth and Development and Schools | Corporate administration and operations | $127,063 | $977 | 2025 |
| Ogunsulire, Mobolaji | Manager, Oral Health | Corporate administration and operations | $121,292 | $469 | 2025 |
| Lang, Jessica | Manager, Population Health Assessment | Corporate administration and operations | $120,912 | $703 | 2025 |
| Annamunthodo, Marcia | Manager, Vaccine Preventable Diseases and Health Equity | Corporate administration and operations | $120,237 | $469 | 2025 |
| Atkinson, Alexis | Manager, Environmental Health | Corporate administration and operations | $119,841 | $484 | 2025 |
| Los, Nicole | Manager, Healthy Growth and Development | Corporate administration and operations | $119,610 | $475 | 2025 |
| Sargent, Dax | Manager, Information Technology | Digital, data and technology | $119,004 | $937 | 2025 |
| Lewis, Katie | Director, Human Resources | Human resources, labour relations and total rewards | $117,435 | $1,268 | 2025 |
| Stryker, Alyssa | Drug Strategy Coordinator | Corporate administration and operations | $112,551 | $884 | 2025 |
| Wood, Jaclyn | Manager, Population Health Assessment | Corporate administration and operations | $112,467 | $420 | 2025 |
| Collins, Pamela | Organizational Development Specialist | Human resources, labour relations and total rewards | $108,702 | $854 | 2025 |
| Hesch, Richard | Public Health Nurse | Clinical health | $102,595 | $703 | 2025 |
| Jose, Antony | Net Developer | Digital, data and technology | $102,549 | $703 | 2025 |
| English, Lindsay | Communications Supervisor | Communications, marketing and public affairs | $102,506 | $673 | 2025 |