| Guttmann, Astrid | Chief Executive Officer | Executive and senior leadership | $399,625 | $2,827 | 2025 |
| Schull, Michael | Chief Executive Officer | Executive and senior leadership | $352,389 | $2,605 | 2025 |
| Stukel, Therese A | Senior Scientist | Academic and research | $277,528 | $300 | 2025 |
| Austin, Peter C | Senior Scientist | Academic and research | $255,649 | $2,342 | 2025 |
| Vermeulen, Marian | Senior Director Research, Data and Financial Services | Academic and research | $244,282 | $2,289 | 2025 |
| Sutradhar, Rinku | Senior Scientist and Program Lead, Cancer | Academic and research | $237,299 | $2,269 | 2025 |
| Paterson, John M | Chief Science Officer | Executive and senior leadership | $236,143 | $2,268 | 2025 |
| Victor, Joseph C | Senior Director, Strategic Partnerships and Digital Services | Digital, data and technology | $229,884 | $2,242 | 2025 |
| Bronskill, Susan | Senior Scientist, Program Lead, Science Advisor | Academic and research | $216,720 | $2,190 | 2025 |
| Cartagena, Rosario G | Chief Privacy and Legal Officer | Executive and senior leadership | $176,463 | $1,660 | 2025 |
| McMahon, Meghan | Associate Scientific Director | Other disclosed roles | $172,913 | $2,032 | 2025 |
| Nadigel, Jessica | Associate Scientific Director | Other disclosed roles | $172,913 | $2,032 | 2025 |
| Franzese, Rosa | Human Resources Director | Human resources, labour relations and total rewards | $170,017 | $2,015 | 2025 |
| Smeed, Todd W | Director, Cybersecurity | Other disclosed roles | $165,874 | $1,999 | 2025 |
| Qiao, Xiaotong | Director, Information Technology | Digital, data and technology | $164,094 | $1,993 | 2025 |
| Borland, Darlene J | Director, Finance | Finance, procurement and audit | $161,775 | $1,984 | 2025 |
| Ratnasingham, Sujitha | Director | Other disclosed roles | $161,764 | $1,985 | 2025 |
| Ho, Minnie M | Director, Data and Analytic Services | Digital, data and technology | $160,473 | $1,979 | 2025 |
| Hayes, Anne T | Director, Partnerships, Health Data Research Network | Academic and research | $155,443 | $1,960 | 2025 |
| Khan, Ferhana B | Director, Data Quality and Information Management | Digital, data and technology | $152,184 | $1,947 | 2025 |
| Taylor, Erika | Director, Research and Analysis | Academic and research | $149,772 | $1,937 | 2025 |
| Stamplecoski, Melissa A | Director, Science Office | Other disclosed roles | $149,250 | $1,936 | 2025 |
| Saskin, Refik | Staff Scientist Data Services | Academic and research | $147,928 | $1,933 | 2025 |
| Siu, Simon C | Senior Manager, Information Technology Infrastructure and Operations | Digital, data and technology | $146,721 | $1,805 | 2025 |
| Nunes De Melo, Magda M | Associate Director | Other disclosed roles | $145,862 | $1,922 | 2025 |
| Fischer, Hadas D | Research Program Manager | Academic and research | $143,796 | $1,916 | 2025 |
| Cooper, Michelle B | Manager, Project Management Office | Corporate administration and operations | $142,052 | $1,908 | 2025 |
| Fang, Jiming | Research Methodologist | Academic and research | $142,052 | $1,908 | 2025 |
| Guan, Jun | Research Methodologist | Academic and research | $138,831 | $1,896 | 2025 |
| Kopp, Alexander | Research Methodologist | Academic and research | $138,831 | $1,896 | 2025 |
| Mumford, Kim | Director, Communications | Communications, marketing and public affairs | $138,638 | $1,105 | 2025 |
| Legacy, Dominique-Michelle | Director, Indigenous Partnerships and Data Analytics | Digital, data and technology | $138,638 | $1,896 | 2025 |
| Chai-Onn, Jason P | Systems Engineer | Digital, data and technology | $135,755 | $1,884 | 2025 |
| Campitelli, Michael A | Staff Scientist | Academic and research | $135,597 | $1,884 | 2025 |
| Ishiguro, Lisa Y | Research Program Manager | Academic and research | $134,901 | $1,881 | 2025 |
| Green, Jennifer F | Managing Legal Counsel, Manager Legal Services | Legal and judiciary | $133,298 | $1,875 | 2025 |
| Liu, Ning | Research Methodologist | Academic and research | $132,059 | $1,869 | 2025 |
| Comartin, David J | Research Program Manager | Academic and research | $132,028 | $1,871 | 2025 |
| Etches, Jacob J | Staff Scientist | Academic and research | $131,722 | $1,869 | 2025 |
| Hoyt, Lesley A | Staff Scientist | Academic and research | $131,722 | $1,869 | 2025 |
| Edwards, Sarah A | Staff Scientist | Academic and research | $131,540 | $1,868 | 2025 |
| Wilton, Andrew S | Research Methodologist | Academic and research | $129,640 | $1,860 | 2025 |
| Karthamada Kalappa, Gangamma | Lead Specialist, Data Science | Digital, data and technology | $129,617 | $1,861 | 2025 |
| Mecredy, Graham C | Staff Scientist | Academic and research | $128,981 | $1,858 | 2025 |
| Li, Ping | Research Methodologist | Academic and research | $128,919 | $1,858 | 2025 |
| Wang, Xuesong | Research Methodologist | Academic and research | $128,710 | $1,856 | 2025 |
| Hipel, Jacob | Systems Engineer | Digital, data and technology | $128,448 | $1,856 | 2025 |
| Tusevljak, Natasa | Research Program Manager | Academic and research | $127,832 | $1,855 | 2025 |
| Li, Yuan | Solutions Architect | Digital, data and technology | $125,789 | $1,846 | 2025 |
| Gandhi, Sima | Research Program Manager | Academic and research | $125,317 | $1,845 | 2025 |
| Lewandoski, Ash-Lei | Senior Legal Counsel, Regulatory Legal Advisor | Legal and judiciary | $125,017 | $1,843 | 2025 |
| Thanabalasingam, Ramanan | Network Architect | Digital, data and technology | $124,732 | $1,842 | 2025 |
| Legere, Laura E | Senior Manager, Public and Comm Engagement, Knowledge Translation | Corporate administration and operations | $124,428 | $1,841 | 2025 |
| Calzavara, Andrew | Associate Research Methodologist | Academic and research | $124,101 | $1,839 | 2025 |
| Ji, Xiang (Sean) | Manager, Data Quality | Digital, data and technology | $123,280 | $1,836 | 2025 |
| Ma, Ying | Lead Specialist, Record Linkage | Other disclosed roles | $123,133 | $1,836 | 2025 |
| Koh, Maria H | Staff Scientist | Academic and research | $123,123 | $1,835 | 2025 |
| Candido, Elisa | Staff Scientist | Academic and research | $122,971 | $2,144 | 2025 |
| Chu, Anna | Associate Research Methodologist | Academic and research | $121,561 | $1,831 | 2025 |
| Wilkinson, Jennifer P | Privacy And Security Audit Specialist | Finance, procurement and audit | $121,561 | $1,831 | 2025 |
| Gozdyra, Piotr | Medical Geographer | Other disclosed roles | $120,826 | $1,827 | 2025 |
| Peshin, Sujata | Portfolio Management Specialist | Other disclosed roles | $120,223 | $1,824 | 2025 |
| Akhile, Ejemen O | Senior Cybersecurity Analyst | Corporate administration and operations | $120,179 | $1,826 | 2025 |
| Milikhina, Marina | Financial Controller | Finance, procurement and audit | $120,009 | $1,823 | 2025 |
| Wu, Caixia | Associate Research Methodologist | Academic and research | $119,029 | $1,820 | 2025 |
| Gavaric, Dragana | Human Resources Business Partner | Human resources, labour relations and total rewards | $118,210 | $1,817 | 2025 |
| Rachlis, Beth | Staff Scientist | Academic and research | $117,295 | $1,814 | 2025 |
| Mondor, Luke | Staff Scientist | Academic and research | $116,764 | $1,812 | 2025 |
| Yu, Bing | Data Quality Specialist | Digital, data and technology | $115,862 | $1,809 | 2025 |
| Thiruchelvam, Devatharshny | Local Lead Analyst | Corporate administration and operations | $115,564 | $1,807 | 2025 |
| Park, Jin-Young | Manager, Facilities | Engineering, planning and infrastructure | $114,993 | $1,805 | 2025 |
| Park, Alison | Algorithms and Data Harmonization Epidemiologist | Digital, data and technology | $113,981 | $1,801 | 2025 |
| Hill, Carl L | Senior Cybersecurity Analyst | Corporate administration and operations | $113,134 | $1,737 | 2025 |
| Lu, Hong | Associate Research Methodologist | Academic and research | $112,758 | $1,796 | 2025 |
| Bai, Li | Associate Research Methodologist | Academic and research | $112,758 | $1,796 | 2025 |
| Chan, Wing C | Associate Research Methodologist | Academic and research | $112,758 | $1,796 | 2025 |
| Novess, Jennafer | Research Program Manager | Academic and research | $112,196 | $1,796 | 2025 |
| Jovellanos, Isaac | Manager, Information Technology Service Desk | Digital, data and technology | $111,873 | $1,793 | 2025 |
| Diong, Christina | Associate Research Methodologist | Academic and research | $111,061 | $1,790 | 2025 |
| Luo, Jin | Senior Research Analyst | Academic and research | $110,961 | $1,790 | 2025 |
| Qiu, Feng | Senior Research Analyst | Academic and research | $110,961 | $1,790 | 2025 |
| Virmani, Shrey | Data Engineer | Digital, data and technology | $109,519 | $1,784 | 2025 |
| Zagorski, Brandon M | Associate Research Methodologist | Academic and research | $109,198 | $1,784 | 2025 |
| Felix, Marvin N | Senior Financial Analyst | Finance, procurement and audit | $108,565 | $1,781 | 2025 |
| Zhang, Bo | Senior Research Analyst | Academic and research | $108,565 | $1,781 | 2025 |
| Li, Qing | Senior Research Analyst | Academic and research | $108,252 | $1,781 | 2025 |
| Li, Shudong | Senior Research Analyst | Academic and research | $107,104 | $1,775 | 2025 |
| Wang, Guannan | Senior Record Linkage Analyst | Corporate administration and operations | $105,983 | $1,772 | 2025 |
| Sumale, Agrepino M | Solutions Architect | Digital, data and technology | $105,341 | $1,768 | 2025 |
| Dvorani, Erind | Associate Research Methodologist | Academic and research | $105,236 | $1,768 | 2025 |
| Duchen, Raquel | Senior Project Manager, Partnerships, Health Data Research Network | Academic and research | $104,736 | $1,766 | 2025 |
| Liu, Ying | Senior Data Quality Analyst | Digital, data and technology | $104,615 | $1,766 | 2025 |
| Martinez Dietsch, Cesar | Cybersecurity Analyst | Corporate administration and operations | $103,153 | $1,761 | 2025 |
| Fu, Longdi | Senior Research Analyst | Academic and research | $103,145 | $1,761 | 2025 |
| Huang, Anjie | Senior Research Analyst | Academic and research | $103,143 | $1,761 | 2025 |
| Ho, Cindy | Senior Research Project Manager | Academic and research | $103,036 | $1,761 | 2025 |
| Pratt, Misty K | Director, Communications | Communications, marketing and public affairs | $102,409 | $1,757 | 2025 |
| Zhang, Yunqi | Data Quality Specialist | Digital, data and technology | $102,166 | $1,756 | 2025 |
| Ling, Vicki (Yushu) | Senior Research Analyst | Academic and research | $102,153 | $1,757 | 2025 |
| Prasad, Treesa J | Corporate Project Manager | Corporate administration and operations | $101,837 | $1,755 | 2025 |