| Radvanyi, Leslie | President and Scientific Director | Executive and senior leadership | $539,745 | $123 | 2025 |
| Williams, Christine | Acting President and Head, Implementation Science | Executive and senior leadership | $395,996 | $1,477 | 2025 |
| Stein, Lincoln | Acting Scientific Director and Head, Adaptive Oncology | Clinical health | $383,287 | $800 | 2025 |
| Simpson, Jared T. | Interim Scientific Director and Principal Investigator | Teaching and school administration | $331,897 | $1,477 | 2025 |
| Uehling, David E. | Interim Scientific Director, Therapeutic Innovation and Drug Discovery | Other disclosed roles | $329,520 | $1,477 | 2025 |
| Goodhand, Peter | Executive Lead | Other disclosed roles | $321,485 | $677 | 2025 |
| Dias D'Souza, Jeanette | Senior Vice President, Group Chief Financial Officer | Executive and senior leadership | $319,995 | $1,477 | 2025 |
| Campos, Robert V. | Senior Director | Other disclosed roles | $256,531 | $1,430 | 2025 |
| Tamarchak, Rebecca L. | Head, Strategy, Governance and Partnerships | Other disclosed roles | $249,995 | $1,477 | 2025 |
| Sutton, David M | Senior Director | Other disclosed roles | $240,446 | $1,424 | 2025 |
| Reimand, Juri | Principal Investigator | Teaching and school administration | $233,643 | $1,384 | 2025 |
| Isaac, Methvin | Senior Scientific Advisor | Other disclosed roles | $229,140 | $1,386 | 2025 |
| Douglas-Prashad, Patricia Michelle | Senior Director | Other disclosed roles | $228,130 | $1,380 | 2025 |
| Simkevitz, Howard | Senior Director | Other disclosed roles | $223,108 | $1,336 | 2025 |
| McKenzie, Donna | Senior Director | Other disclosed roles | $222,020 | $1,371 | 2025 |
| Courtot, Melanie | Senior Director | Other disclosed roles | $217,597 | $1,223 | 2025 |
| Vedadi, Masoud | Senior Scientific Advisor | Other disclosed roles | $209,945 | $1,259 | 2025 |
| Marcellus, Richard C. | Senior Scientific Advisor | Other disclosed roles | $208,752 | $1,258 | 2025 |
| Abelson, Sagi | Principal Investigator | Teaching and school administration | $202,039 | $1,201 | 2025 |
| Wilson, Julie | Director | Other disclosed roles | $197,086 | $1,194 | 2025 |
| Mamai, Ahmed | Scientific Advisor | Other disclosed roles | $190,539 | $591 | 2025 |
| Bayani, Jane | Director | Other disclosed roles | $188,766 | $1,118 | 2025 |
| Spears, Melanie | Director | Other disclosed roles | $188,764 | $1,118 | 2025 |
| Aman, Ahmed | Scientific Advisor | Other disclosed roles | $188,550 | $1,036 | 2025 |
| Limoges, Jacqueline | Chair, Ontario Cancer Research Ethics Board | Academic and research | $184,807 | $0 | 2025 |
| Petrocelli, Teresa | Director | Other disclosed roles | $183,382 | $591 | 2025 |
| Kozlowski, Natascha | Director | Other disclosed roles | $170,510 | $1,033 | 2025 |
| Pai, Shraddha | Principal Investigator | Teaching and school administration | $166,443 | $987 | 2025 |
| Eubank, Jonathon | Associate Director | Other disclosed roles | $163,861 | $987 | 2025 |
| Mason, Michelle | Director | Other disclosed roles | $163,063 | $987 | 2025 |
| Yearwood, Gino A. | Associate Director | Other disclosed roles | $162,236 | $982 | 2025 |
| Brazas, Michelle D. | Director | Other disclosed roles | $161,189 | $976 | 2025 |
| Richardsson, Anders | Associate Director | Other disclosed roles | $160,583 | $952 | 2025 |
| Sundquist, Stephen | Executive Director | Executive and senior leadership | $158,539 | $956 | 2025 |
| Needles, Christopher | Director | Other disclosed roles | $157,560 | $950 | 2025 |
| Chadwick, Dianne | Director | Other disclosed roles | $154,594 | $699 | 2025 |
| Kirsh, Victoria | Scientific Associate | Other disclosed roles | $149,293 | $824 | 2025 |
| Ramnauth, Jailall | Associate Director | Other disclosed roles | $143,905 | $867 | 2025 |
| Taschuk, Morgan L. | Associate Director | Other disclosed roles | $142,829 | $858 | 2025 |
| Feher, Henrich | Architect | Digital, data and technology | $142,522 | $857 | 2025 |
| Sullivan, Jessica A. | Associate Director | Other disclosed roles | $142,080 | $842 | 2025 |
| Prakesch, Michael A. | Principal Research Scientist | Academic and research | $141,798 | $855 | 2025 |
| Laufer, Radoslaw | Principal Research Scientist | Academic and research | $141,794 | $858 | 2025 |
| Smil, David | Principal Research Scientist | Academic and research | $141,138 | $836 | 2025 |
| Perko, Barbara | Associate Director | Other disclosed roles | $140,750 | $852 | 2025 |
| McDonald, Kelly | Senior Program Manager | Corporate administration and operations | $138,363 | $833 | 2025 |
| Lam, Bernard | Associate Director | Other disclosed roles | $137,346 | $827 | 2025 |
| Ptak, Carolyn | Associate Director | Other disclosed roles | $135,856 | $805 | 2025 |
| Subramanian, Pandiaraju | Principal Research Scientist | Academic and research | $135,582 | $804 | 2025 |
| Liu, Yong | Principal Research Scientist | Academic and research | $133,762 | $792 | 2025 |
| Wang, Zezhou | Senior Research Scientist | Academic and research | $133,586 | $805 | 2025 |
| Wong, Yu Hin | Senior Architect | Digital, data and technology | $133,396 | $804 | 2025 |
| Alturmessov, Yelizar | Senior Architect | Digital, data and technology | $130,937 | $753 | 2025 |
| Lall, Ayush | Senior Manager | Corporate administration and operations | $130,250 | $786 | 2025 |
| Yuen, Denis | Developer | Digital, data and technology | $129,398 | $782 | 2025 |
| Cromar, Graham | Senior Manager | Corporate administration and operations | $129,287 | $764 | 2025 |
| Rivera, Leonardo | Senior Architect | Digital, data and technology | $128,871 | $777 | 2025 |
| Falkenberg, Ryan | Team Lead | Other disclosed roles | $128,287 | $773 | 2025 |
| Joseph, Babu | Senior Research Scientist | Academic and research | $127,840 | $389 | 2025 |
| Chan, Brandon | Senior Manager | Corporate administration and operations | $126,858 | $752 | 2025 |
| Tcherkezian, John | Senior Manager | Corporate administration and operations | $126,858 | $752 | 2025 |
| Heisler, Lawrence E. | Senior Manager | Corporate administration and operations | $125,496 | $745 | 2025 |
| Mihaiescu, George | Architect | Digital, data and technology | $124,594 | $734 | 2025 |
| Demaria, Daniel | Developer | Digital, data and technology | $123,941 | $731 | 2025 |
| Wilson, Brian J. | Senior Research Scientist | Academic and research | $123,554 | $1,045 | 2025 |
| Kiyota, Taira | Senior Research Scientist | Academic and research | $123,450 | $746 | 2025 |
| Chan, Manuel H. | Senior Research Scientist | Academic and research | $122,923 | $743 | 2025 |
| Xin, Tao | Senior Research Scientist | Academic and research | $122,923 | $743 | 2025 |
| Chau, Anh | Senior Research Scientist | Academic and research | $122,371 | $739 | 2025 |
| Dokun, Olusola Y. | Senior Manager | Corporate administration and operations | $122,294 | $739 | 2025 |
| Lima Fernandes, Evelyne | Senior Research Scientist | Academic and research | $121,819 | $723 | 2025 |
| Cescon, David | Scientific Director | Other disclosed roles | $121,386 | $0 | 2025 |
| Gibson, Robert J. | Senior Architect | Digital, data and technology | $120,817 | $646 | 2025 |
| Seddon, Geoffrey | Systems Administrator | Digital, data and technology | $120,125 | $697 | 2025 |
| Xiang, Qian | Research Associate | Academic and research | $119,891 | $723 | 2025 |
| Pillai, Patricia | Manager, Human Resources | Human resources, labour relations and total rewards | $119,616 | $721 | 2025 |
| Catton, Caroline Ann | Developer | Digital, data and technology | $119,276 | $720 | 2025 |
| Kato, Diana | Manager, Operations | Corporate administration and operations | $118,796 | $716 | 2025 |
| Barker, Sarah | Senior Program Manager | Corporate administration and operations | $118,641 | $711 | 2025 |
| Velalcazar, Silvia | Senior Manager | Corporate administration and operations | $118,484 | $715 | 2025 |
| Arokium, Marcellus | Senior Manager | Corporate administration and operations | $117,229 | $411 | 2025 |
| Mistry, Rakesh | Architect | Digital, data and technology | $117,083 | $709 | 2025 |
| Haw, Robin A. | Senior Program Manager | Corporate administration and operations | $115,543 | $697 | 2025 |
| Rich, Samantha | Developer | Digital, data and technology | $114,758 | $693 | 2025 |
| Peltekova, Vanya D. | Manager, BioLab | Corporate administration and operations | $114,360 | $678 | 2025 |
| Dos Santos, Patrick | Senior Designer | Other disclosed roles | $114,360 | $690 | 2025 |
| Duarte, Jason | Manager, Facilities | Engineering, planning and infrastructure | $112,927 | $669 | 2025 |
| Aguilar, Marlon | Systems Administrator | Digital, data and technology | $112,567 | $650 | 2025 |
| Bohorquez Martinez, Hugo | Senior Research Scientist | Academic and research | $111,886 | $675 | 2025 |
| De Borja, Maria Aurora | Manager, Research Ethics | Academic and research | $111,636 | $634 | 2025 |
| Bansal, Archana | Senior Manager | Corporate administration and operations | $109,985 | $664 | 2025 |
| Moldovan, Ovidiu Valeriu | Manager, Procurement | Finance, procurement and audit | $109,975 | $531 | 2025 |
| Trinh, Quang | Scientific Associate | Other disclosed roles | $109,765 | $666 | 2025 |
| Mantell, Alexis | Manager, Communications | Communications, marketing and public affairs | $109,267 | $660 | 2025 |
| Wright, Adam John | Architect | Digital, data and technology | $109,250 | $649 | 2025 |
| Baird, Leanne | Manager, Human Resources | Human resources, labour relations and total rewards | $109,098 | $656 | 2025 |
| Miller, Jessica | Manager, Quality Assurance | Corporate administration and operations | $108,207 | $643 | 2025 |
| Li, Shuhan Alexis | Technical Business Analyst | Corporate administration and operations | $107,581 | $647 | 2025 |
| Phillips, Cole | Systems Administrator | Digital, data and technology | $106,561 | $634 | 2025 |
| Punch, Daniel | Manager, Communications | Communications, marketing and public affairs | $106,561 | $631 | 2025 |