| Mercer, Nicola | Medical Officer of Health and Chief Executive Officer | Executive and senior leadership | $356,341 | $5,477 | 2025 |
| Tenenbaum, Matthew | Associate Medical Officer of Health | Other disclosed roles | $317,449 | $676 | 2025 |
| Beveridge, Christopher | Vice President, Health Protection and Emergency Preparedness | Executive and senior leadership | $203,398 | $431 | 2025 |
| Isley, Rita | Vice President, Community Health; Chief Nursing Officer | Executive and senior leadership | $193,593 | $847 | 2025 |
| Wilson, Kyle | Vice President, Information Services and Digital Innovation; Chief Privacy Officer and Chief Information Officer | Executive and senior leadership | $190,968 | $647 | 2025 |
| Kingma, David | Chief Administrative Officer | Executive and senior leadership | $190,968 | $647 | 2025 |
| Herman, Brian | Chief Financial Officer | Executive and senior leadership | $168,327 | $570 | 2025 |
| Rajaram, Emerson | Chief Information Security Officer | Executive and senior leadership | $168,327 | $620 | 2025 |
| Wardach, Patryk | Chief Human Resources Officer | Executive and senior leadership | $168,327 | $570 | 2025 |
| Wong, Phil | Operations Director, Health Protection | Corporate administration and operations | $154,301 | $492 | 2025 |
| Hebden, Lisa | Operations Director, Client Services | Corporate administration and operations | $146,804 | $490 | 2025 |
| Medeiros, Paul | Manager, Environmental Health | Corporate administration and operations | $136,655 | $440 | 2025 |
| Marinko, Lilliana | Manager, Infectious Diseases | Corporate administration and operations | $135,199 | $440 | 2025 |
| Loucks, Camille | Manager, Clinical Services | Clinical health | $133,746 | $440 | 2025 |
| Mulvey, Karen | Manager, Vaccine Preventable Diseases | Corporate administration and operations | $133,687 | $440 | 2025 |
| Pollington, April | Manager, Dental | Corporate administration and operations | $133,335 | $439 | 2025 |
| Vanderlaan, Anna | Manager, Health Promotion, Project Management, and Privacy | Corporate administration and operations | $130,911 | $447 | 2025 |
| Ferguson, Chuck | Manager, Corporate Communications | Communications, marketing and public affairs | $129,319 | $440 | 2025 |
| Agunsoye, Gabriel | Infrastructure Architect | Digital, data and technology | $123,162 | $402 | 2025 |
| Leenders, Shelby | Manager, Infection Control | Corporate administration and operations | $120,638 | $388 | 2025 |
| Angevaare, Justin | Principal Data Scientist | Academic and research | $119,618 | $423 | 2025 |
| Kamati, Kishore | Software Architect | Digital, data and technology | $118,773 | $402 | 2025 |
| Whyte, Michael | Manager, Data and Analytics | Digital, data and technology | $116,382 | $364 | 2025 |
| Byron, Alana | Supervisor, Community Health | Corporate administration and operations | $115,769 | $121 | 2025 |
| Charlebois, Lara | Public Health Nurse | Clinical health | $114,614 | $325 | 2025 |
| Olson, Katrina A. | Manager, Children's Health Services | Corporate administration and operations | $111,731 | $380 | 2025 |
| Alderson, Kyley | Manager, Health Promotion and Project Management | Corporate administration and operations | $111,723 | $380 | 2025 |
| Sciberras, Juliann | Supervisor, Human Resources | Human resources, labour relations and total rewards | $110,897 | $402 | 2025 |
| Trotz-Williams, Lise | Epidemiologist | Other disclosed roles | $110,660 | $377 | 2025 |
| Richardson, Robert | Supervisor, Facilities and Safety | Engineering, planning and infrastructure | $110,660 | $377 | 2025 |
| Taylor, Orecia L. | Public Health Nurse | Clinical health | $108,233 | $325 | 2025 |
| Lahey, Wendy | Public Health Nurse | Clinical health | $107,286 | $475 | 2025 |
| Cheesman, Michelle | Public Health Nurse | Clinical health | $106,433 | $525 | 2025 |
| Armborst, Adriana | Public Health Nurse | Clinical health | $105,430 | $348 | 2025 |
| Besley, Taylor | Supervisor, Community Health | Corporate administration and operations | $104,451 | $354 | 2025 |
| Martin, Danny D. | Public Health Inspector | Protective services | $103,180 | $350 | 2025 |
| Hendry, Crystal | Public Health Inspector | Protective services | $102,956 | $325 | 2025 |
| Coghlin, Rachel | Supervisor, Community Health | Corporate administration and operations | $102,831 | $344 | 2025 |
| Wilson, Hillary | Supervisor, Health Protection | Corporate administration and operations | $102,831 | $348 | 2025 |
| Cater, Heather | Public Health Nurse | Clinical health | $102,721 | $350 | 2025 |
| Durk, Diane | Public Health Inspector | Protective services | $101,658 | $475 | 2025 |
| Coburn, Michael | Public Health Inspector | Protective services | $101,116 | $525 | 2025 |
| Chang, Emily | Public Health Inspector | Protective services | $101,079 | $350 | 2025 |
| Leonov, Silvia | Public Health Inspector | Protective services | $100,966 | $325 | 2025 |
| Maccallum, Denise | Public Health Nurse | Clinical health | $100,531 | $325 | 2025 |
| Rubicini, Michael | Public Health Inspector | Protective services | $100,085 | $337 | 2025 |
| Bortolon, Mitchel | Public Health Inspector | Protective services | $100,046 | $350 | 2025 |